Paracétamol

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Paracétamol, eyebani lisusus bo acétaminophène to APAP, ezali nkisi basalelaka mpo na kosilisa mpasi mpe fièvre.[1] Mingi mpeza basalelaka yango mutu azali koyoka mua mpasi to mpasi mingi te.[1] Preuve ya litomba ya nkisi oyo mpo na bana eza moke mpeza.[2] Mingi mingi batekaka yango elongo na ba nkisi mosusu neti nkisi mpo na miyoyo.[1] Ntango basangisi yango na nkisi mpo na mpasi kouta na opioïde, basalelaka paracétamol mpo na mutu oyo azoyoka mpasi makasi neti mpasi ya cancer na mpe sima na lipaso.[3] Mingi mpeza bamelaka yango na monoko to kobaka yango, ya kotuba tonga na mizisa mpe ezalaka.[1][4] Ba effet nayango ewumelaka kati na ngonga mibale na minei.[4]

Paracétamol ezalaka na mindondo mpeza te soki baseleli yango kolandana na dose oyo esengeli.[5] Mokosa makasi loposo esalemaka mpeza mingi te.[1] Dose ya koleka mpeza ekoki komema liver failure.[1] Emonani neti eza mindondo te na eleko ya zemi mpe ntango ya komelisa mwana libele.[1] Mpon na baye bazali na maladi ya foie, bakoki kokoba kosalela yango kasi ekosengela basalela dose ya moke.[6] Paracétamol etiyami nakati ya ba nkisi eye eyebani bo analgésique, ba nkisi oyo esilisaka to ekitisaka ba mpasi.[4] Nkisi oyo eza na misala minene te ya anti-inflammatoire eye esalaka mpe lolenge nkisi oyo esalaka eyebani mpeza malamu te.[7]

Bakundolaki paracétamol na mobu ya 1877.[8] Yango ezali nkisi oyo batu mingi basalelaka mpo na kosilisa ba mpasi na fièvre ezala na Etats Unis to Eropa.[9] Nkisi oyo ezali na Liste ya ba Nkisi ya Ntina ya OMS, nkisa ya ntina mpeza oyo esengeli kozanga te na ba lopitalo.[10] Paracétamol ezali kozwama bo générique mpe nkombo misisu eye bakosalela mpo nayango na mombongo eza Tylenol and Panadol.[11] Talo mpo na kosomba na mipiko-mipiko eza na se ya 0.01 USD na dose moko.[12] Na Etats Unis talo nayango eza 0.05 USD na dose moko.[1]

References[kokoma | kobɔngisa mosólo]

  1. 1,0 1,1 1,2 1,3 1,4 1,5 1,6 et 1,7 "Acetaminophen". The American Society of Health-System Pharmacists. http://www.drugs.com/monograph/acetaminophen.html. Retrieved Jan 2016. 
  2. Meremikwu, M; Oyo-Ita, A (2002). "Paracetamol for treating fever in children.". The Cochrane database of systematic reviews (2): CD003676. PMID 12076499. 
  3. (en) Scottish Intercollegiate Guidelines Network (SIGN), Guideline 106: Control of pain in adults with cancer, Scotland, National Health Service (NHS),‎ (ISBN 9781905813384, lire en ligne), « 6.1 and 7.1.1 »
  4. 4,0 4,1 et 4,2 (en) Daniel Hochhauser, Cancer and its Management, John Wiley & Sons,‎ 2014 (ISBN 9781118468715, lire en ligne), p. 119
  5. Russell, FM; Shann, F; Curtis, N; Mulholland, K (2003). "Evidence on the use of paracetamol in febrile children.". Bulletin of the World Health Organization 81 (5): 367–72. PMID 12856055. 
  6. Lewis, JH; Stine, JG (June 2013). "Review article: prescribing medications in patients with cirrhosis - a practical guide.". Alimentary pharmacology & therapeutics 37 (12): 1132–56. PMID 23638982. 
  7. (en) Gerard A. McKaympé Matthew R. Walters, Lecture Notes Clinical Pharmacology and Therapeutics., Hoboken, 9th,‎ 2013 (ISBN 9781118344897, lire en ligne), « Non-Opioid Analgesics »
  8. (en) Brent C. Mangus, Michael G. Miller ; with consultant, Kimberly A. Melgarejo, Pharmacology application in athletic training, Philadelphia, PA, F.A. Davis,‎ 2005 (ISBN 9780803620278, lire en ligne), p. 39
  9. (en) Richard V. Aghababian, Essentials of Emergency Medicine, Jones & Bartlett Publishers,‎ (ISBN 978-1-4496-1846-9, lire en ligne), p. 814
  10. "WHO Model List of Essential Medicines" (PDF). World Health Organization. October 2013. http://apps.who.int/iris/bitstream/10665/93142/1/EML_18_eng.pdf?ua=1. Retrieved 22 April 2014. 
  11. (en) Richard J. Hamilton, Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition, Burlington, Ma., 27th,‎ 2013 (ISBN 9781449665869, lire en ligne), p. 12
  12. "Paracetamol". http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=PAR500T&s_year=2014&year=2014&str=500%20mg&desc=Paracetamol&pack=new&frm=TAB-CAP&rte=PO&class_code2=07%2E1%2E&supplement=&class_name=%2802%2E1%2E%29Non-opioids%20and%20non-steroidal%20anti-inflammatory%20medicines%20%28NSAIMs%29%3Cbr%3E%2807%2E1%2E%29For%20treatment%20of%20acute%20migraine%20attack%3Cbr%3E. Retrieved 11 January 2016.